Alnylam initiates Phase II study with ALN-TTRsc for treatment of ATTR Alnylam Pharmaceuticals.

The results of the clinical research showed that ALN-TTRsc administration resulted in robust, constant, and statistically significant knockdown of serum TTR of up to 94 percent. Knockdown of TTR was found to end up being fast, dose-dependent, and durable. ALN-TTRsc was found to be safe and good tolerated in the study generally. Importantly, these human research results were the first ever to be reported for Alnylam's proprietary GalNAc-siRNA conjugate delivery platform, enabling subcutaneous dosing of RNAi therapeutics with a broad therapeutic index. In 2012, Alnylam entered into an exclusive alliance with Genzyme, a Sanofi company, to build up and commercialize RNAi therapeutics, including ALN-TTRsc and patisiran, for the treatment of ATTR in Japan and the broader Asian-Pacific region.Although it is essential to understand that eating a sensible diet may be the key to great health, there are a variety of foods which have been shown to have especially promising health benefits. It is often these superfoods have an especially advanced of beneficial elements that are ideal in ensuring good wellness. Blueberries best the list While there are numerous of tasty and healthy foods that are one of many superfoods, blueberries best any set of that nature continuously.

Other entries from category "reports":

Random entries