Jolie says she wants other women to know their options.

Angelina Jolie tells why she went through more surgery Actress Angelina Jolie revealed today she’s undergone more preventative surgery treatment to reduce her chances of cancer – – by having her ovaries and fallopian tubes removed. Jolie says she wants other women to know their options . Doctors informed Jolie her risk of developing ovarian cancer was 50 %. The 39-year-old acquired inherited a mutation of a gene called BRCA 1, which also dramatically increases the risk of breast cancer. 2 yrs ago she got a dual mastectomy. This month a fake alarm in blood tests led to five anxious times before further screening found no proof cancer.

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The more surprising results were that specific treatments also were linked to leukemic transformation. Use of ESAs or danazol were linked to later development of leukemia, independent of the platelet or blast amounts. Ayalew Tefferi, M.D., principal investigator of the study, and a Mayo Clinic hematologist, cautions that the existing findings are based on retrospective observation and have to be validated in correctly designed prospective studies. Tefferi. The scholarly research evaluated the information of 311 Mayo Clinic patients, seen with major myelofibrosis between 1976 and 2006. Of these patients, at an average follow-up of 27 months, 27 cases of leukemic transformation had been documented.

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