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The 82 patients enrolled in the open-label, single-arm Japan Clinical Oncology Group Study JCOG0901 trial received amrubicin 40 mg/m2 for 3 days on a 21-day routine, for a median of four cycles. All sufferers had experienced no response already, or progression, following treatment with at least one platinum-based regimen, with 51.2 percent previously treated with etoposide and 57.3 percent with irinotecan. Related StoriesMD Anderson research reveals why chemotherapy medications not effective for many pancreatic tumor patientsCornell biomedical engineers develop 'super organic killer cells' to destroy malignancy cells in lymph nodesOvarian cancer patients with a history of oral contraceptive use have better outcomesThe general response rate, defined as an assessed total or partial response individually, was significant highly, at 32.9 percent, compared with a null hypothesis threshold of 10.0 percent or below.

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