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Postdoctoral fellow Brian Altman, PhD, and doctoral student Annie Hsieh, MD, both from the lab of senior author Chi Van Dang, MD, PhD, director Abramson Cancers Center, study body time clock proteins associated with cancer cells. The researchers found that MYC may influence circadian rhythm and fat burning capacity by promiscuously binding to promoter areas in crucial genes for maintaining these daily cycles. Co-first authors Hsieh and Altman, Dang and colleagues report their results this week in Cell Fat burning capacity in advance of the print issue online. This work ties together the analysis of cell fat burning capacity and cancer chronotherapy – If cells don't have to 'rest,' they may replicate all of the right time, without breaks at all.

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